PLATFORM & PIPELINE
PUBLICATIONS
- Stress induces behavioral abnormalities by increasing expression of phagocytic receptor, MERTK, in astrocytes to promote synapse phagocytosis.
- Immunity 2023 July
- Anti-inflammatory clearance of amyloid-β by a chimeric Gas6 fusion protein.
- Nature Medicine 2022 Aug
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A distinct astrocyte subtype in the aging mouse brain characterized by impaired
protein homeostasis. - Nature Aging 2022 Aug
- Stroke subtype-dependent synapse elimination by reactive gliosis in mice.
- Nature Communications 2021 Nov
- Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis.
- Nature 2021 Feb
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Microglial MERTK eliminates phosphatidylserine-displaying inhibitory
post-synapses. - EMBO Journal 2021 May
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In Vitro Engulfment Assay to Measure Phagocytic Activity of Astrocytes Using
Synaptosomes. - Methods Molecular Biology 2019
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Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy
to clear myelin in a mouse model of nerve injury. - Proc. Nat. Acad. Sci. USA. 2017 Sep
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A novel allele-dependent role for APOE in controlling the rate of synapse pruning
by astrocytes. - Proc. Nat. Acad. Sci. USA. 2016 Sep
- Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways.
- Nature 2013 Dec
These papers were published at Stanford University and KAIST by Professor Wonsuk Chung, Scientific Co-founder.